Cheng Lab

Publications

  • Ho J, Puoplo N, Pokharel N, Hirdaramani A, Hanyaloglu AC, Cheng CW. Nutrigenomic underpinnings of intestinal stem cells in inflammatory bowel disease and colorectal cancer development. Front Genet. 2024 Aug 30;15:1349717. PMID: 39280096; PMCID: PMC11393785.
  • Imada S, Khawaled S, Shin H, Meckelmann SW, Whittaker CA, Corrêa RO, Alquati C, Lu Y, Tie G, Pradhan D, Calibasi-Kocal G, Nascentes Melo LM, Allies G, Rösler J, Wittenhofer P, Krystkiewicz J, Schmitz OJ, Roper J, Vinolo MAR, Ricciardiello L, Lien EC, Vander Heiden MG, Shivdasani RA, Cheng CW, Tasdogan A*, Yilmaz ÖH*. Short-term post-fast refeeding enhances intestinal stemness via polyamines. Nature. 2024 Sep;633(8031):895-904. Epub 2024 Aug 21. PMID: 39169180
  • Gebert N., Rahman S., Lewis CA, Ori A*, Cheng CW*. Identifying Cell-Type-Specific Metabolic Signatures Using Transcriptome and Proteome Analyses. Curr Protoc . (2021) Sep;1(9):e245. PMID: 34516047.
  • Calibasi-Kocal G, Mashinchian O, Basbinar Y, Ellidokuz E, Cheng CW* and Yilmaz O*. (*co-corresponding author) Nutritional Control of Intestinal Stem Cells in Homeostasis and Tumorigenesis. (2020). Trends Endocrinol Metab. In press Jan;32(1):20-35. PMID: 33277157
  • Cheng CW, Yilmaz OH, Mihaylova MM. Strategies for Measuring Induction of Fatty Acid Oxidation in Intestinal Stem and Progenitor Cells. (2020). Methods Mol Biol. p53-64. doi: 10.1007/978-1-0716-0747-3_4. PMID: 32705635
  • Cheng CW, Biton M, Haber A, Rickelt S, Butty V, Whary MT, Levine SS, Mino-Kenudson M, Deshpande V, Hynes RO, Fox JG, Regev A and Yilmaz ÖH. Ketone Body Signaling Mediates Intestinal Stem Cell Homeostasis and Adaptation to Diet. (2019).Cell. PMID:31442404.
  • Mihaylova MM*, Cheng CW*, Cao AQ, Tripathi S, Mana MD, Bauer-Rowe KE, Abu-Remaileh M, Clavain L, Erdemir A, Lewis C, Freinkman E, Huang Y, Bell G, Deshpande V, Carmeliet P, Katajisto P, Sabatini DM and Yilmaz ÖH. (*co-first author) Fasting-Activated Fatty Acid Oxidation Enhances Intestinal Stem Cell Function. (2018). Cell Stem Cell. PMID:29727683
  • Cheng CW and Yilmaz ÖH. FAOund the Link: Phospholipid Remodeling and Intestinal Stem Cell Growth and Tumorigenesis. (2018). Cell Stem Cell. PMID:29395049
  • Cheng CW and Yilmaz ÖH. Starving leukemia to induce differentiation. (2017). Nature Medicine. PMID:28060803
  • Cheng CW, Villani V, Buono R, Wei M, Kumar S, Yilmaz OH, Cohen P, Sneddon J, Perin L, and Longo V. Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes. (2017).Cell. PMID:28235195
  • Cheng CW and Yilmaz ÖH. IGFBP3 and T1D: Systemic Factors in Colonic Stem Cell Function and Diabetic Enteropathy. (2015). Cell Stem Cell. PMID:26431180.
  • Cheng CW, Gregor B. Adams, Laura Perin, Min Wei, Xiaoying Zhou, Ben S. Lam, Stefano Da Sacco, Mario Mirisola, David Quinn, Tanya Dorff, John J. Kopchick and Valter D. Longo. Prolonged fasting reduces IGF-1/PKA to promote hematopoietic-stem-cell-based regeneration and reverse immunosuppression. (2014). Cell Stem Cell. PMID: 24905167